Stoichiometry of the 9 10 Nicotinic Cholinergic Receptor
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چکیده
منابع مشابه
Stoichiometry of the 9 10 Nicotinic Cholinergic Receptor
Paola V. Plazas,1 Eleonora Katz,1,2 Marı́a E. Gomez-Casati,1 Cecilia Bouzat,3 and A. Belén Elgoyhen1 1Institute of Investigations in Genetic Engineering and Molecular Biology, National Council of Scientific and Technical Investigations, and 2Department of Physiology, Molecular and Cellular Biology, Faculty of Exact and Natural Sciences, University of Buenos Aires, Buenos Aires 1428, Argentina, a...
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In this study, we report the effects of the quinoline derivatives quinine, its optical isomer quinidine, and chloroquine on 9 10-containing nicotinic acetylcholine receptors (nAChRs). The compounds blocked acetylcholine (ACh)-evoked responses in 9 10-injected Xenopus laevis oocytes in a concentration-dependent manner, with a rank order of potency of chloroquine (IC50 0.39 M) quinine (IC50 0.97 ...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2005
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.3805-05.2005